Background:  Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Carbohydrate sulfotransferase 9 (CHST9), also referred to as GalNAc-4-ST2, catalyzes the transfer of sulfate groups to position four of non-reducing terminal N-acetylgalactosamine (GalNAc) residues of N-glycans and O-glycans. Human CHST9 is strongly expressed in the trachea and murine CHST9 is predominantly expressed in the pituitary. CHST9 belongs to the HNK-1ST family of sulfotransferases and is highly homologous to CHST8. CHST8 and CHST9 have different substrate specificity but both are capable of transfering sulfate to the glycoproteins Lutropin, thyrotropin, Tenascin-R, carbonic anhydratase-VI and proopiomelanocortin.

Description: Rabbit polyclonal to CHST9

Immunogen: KLH conjugated synthetic peptide derived from CHST9

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 52 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.